SCHEMBL1458445

SCHEMBL1458445

C=C(c1ccc(N(CC)CC)cc1)c1ccc(N(CC)CC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 2/20 0.52
MAPK1 P28482 2/20 0.52
RECQL P46063 2/20 0.52
PSMD14 O00487 1/20 0.52
GFER P55789 1/20 0.52
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
MAPT P10636 4/20 0.49
GAA P10253 2/20 0.49
NOX1 Q9Y5S8 2/20 0.49
POLB P06746 2/20 0.49
MCL1 Q07820 1/20 0.49
ALDH3A1 P30838 1/20 0.48
ALDH1A3 P47895 1/20 0.48
KDM4E B2RXH2 2/20 0.47
HSP90AA1 P07900 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609137 0.92 MEN1 (0.63) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL10603474 0.92 MEN1 (0.63) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL17811534 0.89 ALDH1A1 (0.50) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL9502935 0.87 MAPT (0.49) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL10472828 0.86 POLB (0.49) ALDH1A1L3MBTL1TSHRMAPK1KMT2A
SCHEMBL10473325 0.85 MEN1 (0.42) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL611731 0.84 MAPT (0.51) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL10472157 0.83 IGLV6-57 (0.42) ALDH1A1L3MBTL1TDP1CYP3A4TSHR
SCHEMBL11648271 0.83 ALDH1A1 (0.56) ALDH1A1L3MBTL1TDP1MAPK1MEN1
SCHEMBL7666185 0.83 ALDH1A1 (0.48) ALDH1A1L3MBTL1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1734060-B1 MODIFIED CONJUGATED DIENE POLYMER, POLYMERIZATION INITIATOR, PROCESSES FOR PRODUCING THESE, AND RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-03-06 EP claimed
US-7767774-B2 Silyl-diamine initiators for anionic polymerization of 1,3-butadiene and styrene, and rubber compositions BRIDGESTONE CORPORATION (JP) 2010-08-03 US claimed
US-20080033110-A1 Modified Conjugated Diene Polymer, Polymerization Intitiator, Method of Producing the Same, and Rubber Composition BRIDGESTONE CORPORATION (JP) 2008-02-07 US claimed
EP-1734060-A1 MODIFIED CONJUGATED DIENE POLYMER, POLYMERIZATION INITIATOR, PROCESSES FOR PRODUCING THESE, AND RUBBER COMPOSITION Bridgestone Corporation (JP) 2006-12-20 EP claimed
US-3986880-A NON-SILVER, LEUCO DYES, PLASTICIZERS, TRIPHENYLCARBINOL, AND ALCOHOLS OR PHENOLS HORIZONS INCORPORATED A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-10-19 US claimed
JP-10182998-A None JP disclosed
EP-3858877-B1 POLYFUNCTIONAL VINYL AROMATIC COPOLYMER AND METHOD FOR MANUFACTURING SAME, COPOLYMER RUBBER OBTAINED THEREFROM, RUBBER COMPOSITION, RUBBER CROSSLINKED MATERIAL, AND TIRE MEMBER NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-05-27 EP disclosed
CN-119912344-A Ozone protection auxiliary agent for dynamic rubber, preparation method and application thereof, and rubber 株洲时代新材料科技股份有限公司 2025-05-02 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
WO-2024225452-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER 旭化成株式会社 2024-10-31 WO disclosed
WO-2024225378-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER 旭化成株式会社 2024-10-31 WO disclosed
US-12037427-B2 Polyfunctional vinyl aromatic copolymer and method for manufacturing same, copolymer rubber obtained therefrom, rubber composition, rubber crosslinked material, and tire member NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-07-16 US disclosed
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0161457-A2 Tetra(dialkylaminophenyl)cyanines, their preparation and their use BASF Aktiengesellschaft (DE) 1985-11-21 EP disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed
US-4055430-A Light sensitive material containing an ethylene compound dye former, an organic polymer compound containing chlorine and a plasticizer FUJI PHOTO FILM CO., LTD. (JA) 1977-10-25 US disclosed