SCHEMBL9502935

SCHEMBL9502935

C=C(c1ccc(OC)cc1)c1ccc(N(CC)CC)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
ALDH1A1 P00352 5/20 0.49
GAA P10253 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPK1 P28482 2/20 0.49
GFER P55789 2/20 0.49
NR1I2 O75469 1/20 0.47
KDM4E B2RXH2 3/20 0.44
CNR2 P34972 5/20 0.44
CNR1 P21554 3/20 0.44
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
KMT2A Q03164 1/20 0.42
RCE1 Q9Y256 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GSK3B P49841 1/20 0.41
PSMD14 O00487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458445 0.87 ALDH1A1 (0.52) MAPTALDH1A1GAAMAPK1GFER
SCHEMBL1263095 0.85 ALDH1A1 (0.60) MAPTALDH1A1GAASMN1; SMN2MAPK1
SCHEMBL10472828 0.85 POLB (0.49) MAPTALDH1A1MAPK1KDM4ELMNA
SCHEMBL9750095 0.84 HDAC3 (0.44) MAPTALDH1A1GAASMN1; SMN2NR1I2
SCHEMBL2496427 0.83 MAPT (0.56) MAPTALDH1A1GAASMN1; SMN2MAPK1
SCHEMBL10473951 0.82 KMT2A (0.51) MAPTALDH1A1GAASMN1; SMN2MAPK1
SCHEMBL10425412 0.81 ALDH1A1 (0.48) MAPTALDH1A1GAASMN1; SMN2MAPK1
SCHEMBL3277627 0.81 MAPT (0.59) MAPTALDH1A1SMN1; SMN2MAPK1NR1I2
SCHEMBL609137 0.80 MEN1 (0.63) MAPTALDH1A1GAAMAPK1GFER
SCHEMBL10603474 0.80 MEN1 (0.63) MAPTALDH1A1GAAMAPK1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377406-B1 PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL CIBA-GEIGY AG (CH) 1993-06-09 EP disclosed
EP-0242170-B1 DIVINYL COMPOUNDS AND CHROMOGENIC RECORDING-MATERIAL PREPARED BY USE THEREOF YAMADA CHEMICAL CO., LTD. (JP) 1991-09-18 EP disclosed
US-5013707-A Pressure- or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1991-05-07 US disclosed
EP-0377406-A1 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1990-07-11 EP disclosed
US-4835291-A Divinyl compounds and chromogenic recording-material prepared by using thereof YAMADA CHEMICAL CO., LTD. (JP) 1989-05-30 US disclosed
EP-0242170-A2 Divinyl compounds and chromogenic recording-material prepared by use thereof YAMADA CHEMICAL CO., LTD. (JP) 1987-10-21 EP disclosed