Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17811467 | 0.92 | MEN1 (0.47) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL609137 | 0.89 | MEN1 (0.63) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL1458445 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL609060 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL10603474 | 0.81 | MEN1 (0.63) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL17811466 | 0.79 | MEN1 (0.78) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL20306694 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL14174046 | 0.78 | TSHR (0.51) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL30100935 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL9502935 | 0.77 | MAPT (0.49) | ALDH1A1MEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005869-B2 | Polymerisation initiators | TRINSEO EUROPE GMBH (CH) | 2018-06-26 | — | — | US | disclosed |
| US-10005869-B2 | Polymerisation initiators | TRINSEO EUROPE GMBH (CH) | 2018-06-26 | — | — | US | disclosed |
| EP-3024855-B1 | POLYMERISATION INITIATORS | TRINSEO EUROPE GMBH (CH) | 2017-05-31 | — | — | EP | disclosed |
| US-20160159956-A1 | Polymerisation Initiators | TRINSEO EUROPE GMBH (CH) | 2016-06-09 | — | — | US | disclosed |
| US-20160159956-A1 | Polymerisation Initiators | TRINSEO EUROPE GMBH (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005869-B2 | Polymerisation initiators | ELOVL5, ELOVL3, ELOVL1 | ALDH1A1 3863/4885MEN1 3319/4885KMT2A 2066/4885 |
| US-20160159956-A1 | Polymerisation Initiators | ELOVL5, ELOVL3, ELOVL1 | ALDH1A1 3863/4885MEN1 3319/4885KMT2A 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.