⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873225 | 1.00 | HIF1A (0.42) | — | |
| Thiomorpholine SCHEMBL2273 | 1.00 | — | — | |
| Thiomorpholine SCHEMBL93637 | 1.00 | HIF1A (0.42) | — | |
| Thiomorpholine SCHEMBL8707518 | 0.96 | — | — | |
| Thiomorpholine SCHEMBL253450 | 0.96 | — | — | |
| SCHEMBL19621386 | 0.96 | HIF1A (0.39) | — | |
| SCHEMBL1615244 | 0.96 | HIF1A (0.39) | — | |
| Thiomorpholine SCHEMBL6608263 | 0.96 | — | — | |
| SCHEMBL1781384 | 0.96 | — | — | |
| Piperazine SCHEMBL1063977 | 0.96 | HIF1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 849 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347577-A1 | KC2-TYPE LIPIDS | Nanovation Therapeutics Inc. (CA) | 2024-04-10 | — | — | EP | claimed |
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-111448190-B | Substituted indole compounds | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | claimed |
| CN-112778282-B | Pyrimidine micromolecule compound and application thereof | 温州医科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-113521079-A | Use of IRAK4 inhibitors for the treatment of ALI/ARDS | 上海领泰生物医药科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| EP-3849538-A1 | COMBINATION THERAPIES | Mirati Therapeutics, Inc. (US) | 2021-07-21 | — | — | EP | claimed |
| CN-112778282-A | Pyrimidine micromolecule compound and application thereof | 温州医科大学 | 2021-05-11 | — | — | CN | claimed |
| CN-109438447-B | Preparation method and application of 5, 7-dihydro-6H-pyrrolo [2,3-d ] pyrimidine-6-ketone derivative | 北京工业大学 | 2020-10-16 | — | — | CN | claimed |
| CN-111448190-A | Substituted indole compounds | 百时美施贵宝公司 | 2020-07-24 | — | — | CN | claimed |
| WO-2020055756-A1 | COMBINATION THERAPIES | Mirati Therapeutics, Inc. (US) | 2020-03-19 | — | — | WO | claimed |
| EP-0653208-A2 | Pharmaceutical agents for treatment or prevention of sunburn | PFIZER INC. (US) | 1995-05-17 | — | — | EP | claimed |
| EP-0633886-A1 | PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES | PHARMACIA & UPJOHN COMPANY (US) | 1995-01-18 | — | — | EP | claimed |
| EP-0627221-A2 | Substance P antagonists for the treatment of emesis | PFIZER INC. (US) | 1994-12-07 | — | — | EP | claimed |
| WO-1994020500-A1 | SPIROAZACYCLIC DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1994-09-15 | — | — | WO | claimed |
| US-5340826-A | Pharmaceutical agents for treatment of urinary incontinence | PFIZER INC. (US) | 1994-08-23 | — | — | US | claimed |
| EP-0610021-A1 | Pharmaceutical agents for treatment of urinary incontinence | PFIZER INC. (US) | 1994-08-10 | — | — | EP | claimed |
| WO-1994003445-A1 | 3-BENZYLAMINO-2-PHENYL-PIPERIDINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-02-17 | — | — | WO | claimed |
| WO-1993020078-A1 | PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES | THE UPJOHN COMPANY (US) | 1993-10-14 | — | — | WO | claimed |
| EP-0171005-B1 | XANTHINYLMETHYLTHIAZOLIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1989-11-23 | — | — | EP | claimed |
| EP-0171005-A2 | Xanthinylmethylthiazolidines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1986-02-12 | — | — | EP | claimed |