Thiomorpholine

Thiomorpholine

SCHEMBL2273

C1CSCCN1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873225 1.00 HIF1A (0.42)
Thiomorpholine SCHEMBL145846 1.00
Thiomorpholine SCHEMBL93637 1.00 HIF1A (0.42)
Thiomorpholine SCHEMBL8707518 0.96
Thiomorpholine SCHEMBL253450 0.96
SCHEMBL19621386 0.96 HIF1A (0.39)
SCHEMBL1615244 0.96 HIF1A (0.39)
Thiomorpholine SCHEMBL6608263 0.96
SCHEMBL1781384 0.96
Piperazine SCHEMBL1063977 0.96 HIF1A (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 99185 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 EP claimed
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIV DE MONTREAL (CA) 2026-05-21 US claimed
EP-4105216-B1 DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-05-20 EP claimed
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases THE UNIVERSITY OF NOTTINGHAM (GB) 2026-05-19 US claimed
CN-119875072-B Temperature-inhibiting type anti-cracking concrete waterproof agent and preparation method thereof 中交第四航务工程局有限公司 2026-05-19 CN claimed
CN-122010969-A Aminated 20 (S) -10, 11-difluoro methylenedioxy camptothecin derivative, and preparation method and application thereof 浙江工业大学 2026-05-12 CN claimed
US-20260115216-A1 NUCLEIC ACID PRECURSOR KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2026-04-30 US claimed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US claimed
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LTD (GB) 2026-04-02 US claimed
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 EP claimed
US-3974275-A 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US claimed
US-3970647-A Bis-(triazinylamino)stilbene compounds SANDOZ LTD. (CH) 1976-07-20 US claimed
US-3969349-A Vulcanization of rubber with phosphoro triazine sulfides MONSANTO COMPANY (US) 1976-07-13 US claimed
US-3957987-A ANIMAL FEEDS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US claimed
US-3956492-A SEDATIVES, MUSCLE RELAXANTS, TRANQUILIZERS, ANTICONVULSANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-05-11 US claimed
US-3951963-A 0-(Substituted-aminoalkyl)-5-nitroimidazole-(2)-aldoximes HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed
US-3946009-A ADRENERGIC BLOCKING AGENTS MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1976-03-23 US claimed
US-3939268-A 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents BOEHRINGER INGELHEIM GMBH (DT) 1976-02-17 US claimed
US-3934017-A Anthelmintic composition and method utilizing isothiocyanobenzazoles active ingredients CIBA-GEIGY CORPORATION (US) 1976-01-20 US claimed
US-3933813-A Process for the production of mercaptoethyl containing compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-01-20 US claimed