Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiomorpholine SCHEMBL2273 | 1.00 | — | — | |
| Thiomorpholine SCHEMBL145846 | 1.00 | — | — | |
| Thiomorpholine SCHEMBL93637 | 1.00 | HIF1A (0.42) | HIF1AMAPTPDE4AKDRCXCR4 | |
| Thiomorpholine SCHEMBL8707518 | 0.96 | — | — | |
| Thiomorpholine SCHEMBL253450 | 0.96 | — | — | |
| SCHEMBL19621386 | 0.96 | HIF1A (0.39) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL1615244 | 0.96 | HIF1A (0.39) | HIF1AMAPTPDE4AKDRCXCR4 | |
| Thiomorpholine SCHEMBL6608263 | 0.96 | — | — | |
| SCHEMBL1781384 | 0.96 | — | — | |
| Piperazine SCHEMBL1063977 | 0.96 | HIF1A (0.50) | HIF1AMAPTPDE4AKDRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064956-A | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1991-11-12 | — | — | US | claimed |
| US-5064956-A | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1991-11-12 | — | — | US | disclosed |