Thiomorpholine

Thiomorpholine

SCHEMBL93637

C1CSCCN1.C1CSCCN1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.42
MAPT P10636 1/20 0.42
PDE4A P27815 1/20 0.42
KDR P35968 1/20 0.42
CXCR4 P61073 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873225 1.00 HIF1A (0.42) HIF1AMAPTPDE4AKDRCXCR4
Thiomorpholine SCHEMBL2273 1.00
Thiomorpholine SCHEMBL145846 1.00
Thiomorpholine SCHEMBL8707518 0.96
Thiomorpholine SCHEMBL253450 0.96
SCHEMBL19621386 0.96 HIF1A (0.39) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL1615244 0.96 HIF1A (0.39) HIF1AMAPTPDE4AKDRCXCR4
Thiomorpholine SCHEMBL6608263 0.96
SCHEMBL1781384 0.96
Piperazine SCHEMBL1063977 0.96 HIF1A (0.50) HIF1AMAPTPDE4AKDRCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210402381-A1 RUBBER COMPOSITIONS AND METHODS KREUTZ FERNANDO THOME (BR) 2021-12-30 US claimed
US-20040180985-A1 Tack free surface cures of polymers by organic peroxides in the presence of air ARKEMA INC. 2004-09-16 US claimed
US-6747099-B1 BIS-, TRI- AND HIGHER POLY-MALEIMIDES, SILICONE ELASTOMER, P-PHENYLENEDIAMINE BASED ANTIOZONANTS, SULFUR VULCANIZATION ACCELERANT ATOFINA CHEMICALS, INC. 2004-06-08 US claimed
CN-1336939-A Tack-free surface curing of polymers by organic peroxides in the presence of air ATOFINA CHEM INC (US) 2002-02-20 CN claimed
CN-118284675-A Adhesive composition, organic fiber-rubber composite material, rubber article, and tire 株式会社普利司通 2024-07-02 CN disclosed
CN-118265761-A Adhesive composition, organic fiber material, rubber article, organic fiber-rubber composite, and tire 株式会社普利司通 2024-06-28 CN disclosed
WO-2024122390-A1 ADHESIVE AGENT COMPOSITION, ORGANIC FIBER, ORGANIC FIBER-RUBBER COMPOSITE MATERIAL, RUBBER ARTICLE, AND TIRE 株式会社ブリヂストン 2024-06-13 WO disclosed
US-11987730-B2 Waterbased one coat adhesive composition DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2024-05-21 US disclosed
US-20240150628-A1 ADHESIVE COMPOSITION, AND RESIN MATERIAL, RUBBER ARTICLE, ORGANIC FIBER-RUBBER COMPOSITE, AND TIRE USING SAME BRIDGESTONE CORPORATION (JP) 2024-05-09 US disclosed
US-20240117224-A1 ADHESIVE COMPOSITION FOR ORGANIC FIBER, ORGANIC FIBER-RUBBER COMPOSITE, AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-11 US disclosed
WO-2024024247-A1 ADHESIVE COMPOSITION, ORGANIC FIBROUS MATERIAL, RUBBER ARTICLE, ORGANIC FIBER/RUBBER COMPOSITE, AND TIRE 株式会社ブリヂストン 2024-02-01 WO disclosed
WO-2024014452-A1 RUBBER REINFORCEMENT FIBER TREATMENT AGENT, RUBBER REINFORCEMENT FIBER TREATMENT AGENT KIT, RUBBER REINFORCEMENT FIBER MANUFACTURING METHOD, RUBBER REINFORCEMENT FIBER, AND RUBBER PRODUCT 明成化学工業株式会社 2024-01-18 WO disclosed
US-4960829-A CURABLE BLEND OF HIGH MOLECULAR WEIGHT POLYMER, ETHYLENE-ALPHA-OLEFIN-NONCONJUGATED POLYENE TERPOLYMER AND CURATIVE UNIROYAL CHEMICAL COMPANY, INC. (US) 1990-10-02 US disclosed
EP-0219446-B1 PROCESS FOR THE PREPARATION OF N-TETRATHIODIMORPHOLINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-03-14 EP disclosed
EP-0344380-A2 Elastomeric composition having increased ozone resistance UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-12-06 EP disclosed
US-4851469-A RUBBER, RESORCIN, HEXAMETHYLENEDIAMINE, MERCAPTOTRIAZINE THE YOKOHAMA RUBBER CO., LTD. (JP) 1989-07-25 US disclosed
US-4843128-A CURED BLEND OF HIGH AND LOW MOLECULAR WEIGHT EPDM TER, UNSATURATED RUBBER, AND QUINOLINE ANTIDEGRADANT; PRECISION MOLDED PARTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-06-27 US disclosed
EP-0246745-A2 Elastomeric composition UNIROYAL CHEMICAL COMPANY, Inc. (US) 1987-11-25 EP disclosed
EP-0219446-A1 Process for the preparation of N-tetrathiodimorpholine THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-04-22 EP disclosed
US-4621139-A Process for the preparation of N-tetrathiodimorpholine THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-11-04 US disclosed