Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766559 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPSR1TSHRUBE2M | |
| SCHEMBL5134793 | 0.72 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPSR1TSHRUBE2M | |
| SCHEMBL4769015 | 0.69 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPSR1TSHRUBE2M | |
| SCHEMBL5134630 | 0.66 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPSR1TSHRTAS2R14 | |
| SCHEMBL1740555 | 0.65 | TAAR1 (0.55) | ALDH1A1SMN1; SMN2NPSR1TSHRCYP3A4 | |
| SCHEMBL17072329 | 0.64 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPSR1TSHRTAS2R14 | |
| SCHEMBL9788827 | 0.64 | TRPM8 (0.62) | ALDH1A1SMN1; SMN2NPSR1TSHRTAS2R14 | |
| SCHEMBL5136876 | 0.63 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2NPSR1TSHRFAAH | |
| SCHEMBL1041553 | 0.63 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGD | |
| SCHEMBL14417369 | 0.63 | TSHR (0.63) | ALDH1A1SMN1; SMN2NPSR1TSHRTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027158-A1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION | 2007-02-01 | — | — | US | disclosed |
| US-20070027158-A1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027158-A1 | High affinity small molecule C5a receptor modulators | C3AR1, C5AR1, C5AR2 | ALDH1A1 4042/4885SMN1; SMN2 4522/4885NPSR1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.