SCHEMBL14586641

SCHEMBL14586641

Cc1ccc(Oc2ccc(NC(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.48
ALDH1A1 P00352 5/20 0.47
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
ALOX12 P18054 2/20 0.45
LMNA P02545 2/20 0.45
ALOX15 P16050 2/20 0.45
TSHR P16473 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.45
RECQL P46063 1/20 0.45
ATM Q13315 1/20 0.45
HSD17B10 Q99714 1/20 0.45
FFAR1 O14842 1/20 0.44
MMP13 P45452 2/20 0.43
HTR2A P28223 1/20 0.42
SLC6A4 P31645 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3530110 0.91 TDP1 (0.54) ALDH1A1TDP1MAPTALOX12LMNA
SCHEMBL1454276 0.87 TDP1 (0.59) ALDH1A1TDP1POLBMAPTALOX12
SCHEMBL13302607 0.83 TDP1 (0.64) ALDH1A1TDP1MAPTALOX12LMNA
SCHEMBL24648994 0.83 NPC1 (0.64) ALDH1A1MAPTLMNAALOX15TSHR
SCHEMBL22967630 0.82 ALDH1A1 (0.57) ALDH1A1TDP1POLBALOX12L3MBTL1
SCHEMBL22967371 0.82 CA2 (0.57) ALDH1A1TDP1MAPTALOX12LMNA
SCHEMBL22967574 0.82 L3MBTL1 (0.47) ALDH1A1TDP1POLBMAPTALOX12
SCHEMBL5583833 0.82 ALDH1A1 (0.56) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL13804604 0.81 HTR2A (0.42) HTR2ASLC6A4KCNH2SCN5ASCN9A
SCHEMBL675141 0.80 TDP1 (0.68) ALDH1A1TDP1MAPTALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed