Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.89 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.89 |
| ▸ | ADRA1D | P25100 | 14/20 | 0.89 |
| ▸ | HRH1 | P35367 | 2/20 | 0.89 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658901 | 0.94 | ADRA1A (1.00) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL6954383 | 0.94 | ADRA1A (1.00) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7068045 | 0.89 | ADRA1A (0.76) | ADRA1AADRA1BADRA1DHRH1MCHR1 | |
| SCHEMBL5663201 | 0.89 | ADRA1A (0.76) | ADRA1AADRA1BADRA1DHRH1MCHR1 | |
| SCHEMBL7068048 | 0.89 | ADRA1A (0.76) | ADRA1AADRA1BADRA1DHRH1MCHR1 | |
| SCHEMBL6961810 | 0.86 | ADRA1A (0.82) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7226018 | 0.83 | ADRA1A (0.80) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7952342 | 0.78 | ADRA1A (0.72) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7966480 | 0.78 | ADRA1A (0.72) | ADRA1AADRA1BADRA1DHRH1ADRA2A | |
| SCHEMBL7962040 | 0.78 | ADRA1A (0.72) | ADRA1AADRA1BADRA1DHRH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | ADRA1A 46/4885ADRA1B 56/4885ADRA1D 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.