SCHEMBL14588243

SCHEMBL14588243

CCOc1ccc(OCF)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.74
TDP1 Q9NUW8 2/20 0.58
TSHR P16473 1/20 0.58
LTA4H P09960 2/20 0.54
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
PARP10 Q53GL7 1/20 0.48
RELA Q04206 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Diethoxybenzene SCHEMBL124015 0.86 NQO1 (1.00) NQO1TDP1TSHRLTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL28186701 0.86 NQO1 (1.00) NQO1TDP1TSHRLTA4HKDM4E
SCHEMBL26128025 0.86 NQO1 (0.47) NQO1TDP1TSHRLTA4HALDH1A1
1,4-Diethoxybenzene SCHEMBL11794798 0.83 NQO1 (0.93) NQO1TDP1TSHRLTA4HKDM4E
SCHEMBL15958746 0.82 NQO1 (0.70) NQO1TDP1TSHRLTA4HLMNA
1,4-Diethoxybenzene SCHEMBL27616183 0.80 NQO1 (0.88) NQO1TDP1TSHRLTA4HKDM4E
SCHEMBL13663678 0.80 LTA4H (0.55) NQO1LTA4HMEN1LMNACYP1A2
SCHEMBL765494 0.80 SMN1; SMN2 (0.48) NQO1TDP1LMNAKMT2AALDH1A1
SCHEMBL16385726 0.79 CA1 (0.58) TDP1TSHRCA12CA1CA2
SCHEMBL12460672 0.79 DRD2 (0.48) NQO1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed