Fluoride

Fluoride

SCHEMBL27620141

F.Nc1ccc2cc(N)ccc2c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
CYP3A4 P08684 5/20 0.72
HSD17B10 Q99714 3/20 0.72
CASP1 P29466 4/20 0.68
CASP7 P55210 2/20 0.68
HBB P68871 2/20 0.68
HIF1A Q16665 2/20 0.68
ALOX15 P16050 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
KDM4E B2RXH2 5/20 0.65
MAPT P10636 5/20 0.65
HTT P42858 4/20 0.52
LMNA P02545 3/20 0.52
F2 P00734 1/20 0.52
CHRM2 P08172 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
ADORA3 P0DMS8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367325 0.96 ALDH1A1 (0.77) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL145891 0.96 ALDH1A1 (0.77) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL2893484 0.90 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL29165604 0.90 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL30413338 0.90 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL442351 0.90 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL3412594 0.90 ALDH1A1 (0.78) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL202182 0.86 ALDH1A1 (0.72) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL29468144 0.86 ALDH1A1 (0.72) ALDH1A1CYP3A4HSD17B10CASP1CASP7
Naphthylamine SCHEMBL76713 0.84 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100478364-C Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2009-04-15 CN disclosed
CN-1732189-A Ethylene polymer and molded article obtained therefrom MITSUI CHEMICALS INC (JP) 2006-02-08 CN disclosed