Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865861 | 0.72 | CYP2C9 (0.43) | PTGS2CYP2E1CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL8899193 | 0.71 | RAB9A (0.49) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL676678 | 0.71 | HPGDS (0.56) | PTGS2PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL3423365 | 0.70 | CYP2A6 (0.66) | PTGS2CYP2A6HPGDSSYKKDM4E | |
| SCHEMBL14268975 | 0.70 | CYP2C9 (0.48) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL25406780 | 0.70 | NPC1 (0.42) | PTGS2CYP2C9CYP2C19PIK3CDPIK3CA | |
| SCHEMBL30567671 | 0.70 | NPC1 (0.42) | PTGS2CYP2C9CYP2C19PIK3CDPIK3CA | |
| SCHEMBL15498024 | 0.70 | HPGDS (0.47) | PTGS2CYP2A6PIK3CDPIK3CAPIK3CB | |
| SCHEMBL15025716 | 0.69 | HPGDS (0.50) | PTGS2CYP2A6PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17051516 | 0.69 | HPGDS (0.54) | PTGS2PIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163924-B2 | Ketolide derivatives | CHIRON CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |