Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 8/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 4/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627061 | 0.84 | L3MBTL1 (0.45) | TSHRELOVL6HTR2AGRIN1GRIN2B | |
| SCHEMBL14591897 | 0.76 | UCHL1 (0.44) | TSHRCTSSCTSLCTSBCTSK | |
| SCHEMBL14591931 | 0.74 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL25066083 | 0.74 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL21142519 | 0.74 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL25760130 | 0.70 | HRH3 (0.40) | PIK3CDKCNH2 | |
| SCHEMBL25760129 | 0.70 | GBA1 (0.41) | GRIN2BKCNH2 | |
| SCHEMBL14591895 | 0.70 | SLC6A2 (0.47) | PIK3CDGRIN1GRIN2B | |
| SCHEMBL12049945 | 0.70 | HTR2A (0.50) | TSHRELOVL6HTR2AL3MBTL1KCNH2 | |
| SCHEMBL7129560 | 0.68 | TSHR (0.65) | TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |