Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129555 | 1.00 | TSHR (0.65) | TSHRL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7118457 | 0.84 | L3MBTL1 (0.50) | TSHRL3MBTL1KMT2AALDH1A1ACHE | |
| SCHEMBL7118462 | 0.84 | L3MBTL1 (0.50) | TSHRL3MBTL1KMT2AALDH1A1ACHE | |
| SCHEMBL21465092 | 0.84 | L3MBTL1 (0.50) | TSHRL3MBTL1KMT2AALDH1A1ACHE | |
| SCHEMBL7117845 | 0.83 | L3MBTL1 (0.54) | TSHRL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7117834 | 0.83 | L3MBTL1 (0.54) | TSHRL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7117840 | 0.83 | L3MBTL1 (0.54) | TSHRL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7125321 | 0.83 | TRPA1 (0.48) | TSHRL3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL27331238 | 0.83 | TSHR (0.66) | TSHRL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7125327 | 0.83 | TRPA1 (0.48) | TSHRL3MBTL1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | TSHR 2216/4885L3MBTL1 4877/4885KMT2A 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.