Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.48 |
| ▸ | FLT3 | P36888 | 8/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626754 | 0.88 | EPHB3 (0.58) | ITGB1ITGA4EPHB3KDM4ECSNK2A1 | |
| SCHEMBL2432131 | 0.86 | EPHB3 (0.60) | ITGB1ITGA4EPHB3CSNK2A1FLT3 | |
| SCHEMBL14591889 | 0.86 | EPHB3 (0.56) | ITGB1ITGA4EPHB3KDM4ECSNK2A1 | |
| SCHEMBL27596530 | 0.83 | EPHB3 (0.61) | ITGB1ITGA4EPHB3CSNK2A1FLT3 | |
| SCHEMBL72295 | 0.82 | PKM (0.54) | ITGB1ITGA4KDM4ENPC1ALDH1A1 | |
| SCHEMBL14491705 | 0.81 | ITGB1 (0.55) | ITGB1ITGA4KDM4EFLT3NPC1 | |
| SCHEMBL12327298 | 0.81 | KDM4E (0.44) | ITGB1ITGA4KDM4ENPC1RAB9A | |
| SCHEMBL14592356 | 0.78 | SMN1; SMN2 (0.44) | ITGB1ITGA4NPC1RAB9ALMNA | |
| SCHEMBL27578649 | 0.78 | EPHB3 (0.58) | ITGB1ITGA4EPHB3KDM4ECSNK2A1 | |
| SCHEMBL2432642 | 0.77 | EPHB3 (0.54) | ITGB1ITGA4EPHB3CSNK2A1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471838-C | VLA-4 inhibitors | DAIICHI SEIYAKU CO (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-100396680-C | Vla-4 inhibitors | DAICHI PHARMACEUTICAL CO LTD (JP) | 2008-06-25 | — | — | CN | disclosed |
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| CN-1699363-A | Vla-4 inhibitors | DAICHI PHARMACEUTICAL CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| CN-1483024-A | Vla-4 inhibitors | ��һ��������ҩ��ʽ���� | 2004-03-17 | — | — | CN | disclosed |