Imidazole

Imidazole

SCHEMBL145932

CC(=O)O.c1c[nH]cn1

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL29411697 1.00 ALDH1A1 (0.65)
Imidazole SCHEMBL30320112 1.00 ALDH1A1 (0.65)
Imidazole SCHEMBL28966030 1.00 ALDH1A1 (0.65)
Imidazole SCHEMBL29188028 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL29365438 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL28213689 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL2256134 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL3639063 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL28796723 0.98 ALDH1A1 (0.62)
Imidazole SCHEMBL27735299 0.98 ALDH1A1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059636-A High slump-retaining type polycarboxylate superplasticizer and preparation method thereof 广东六合新型建材有限公司 2026-05-19 CN claimed
EP-4701438-A1 COMPOSITIONS AND METHODS FOR IMPROVING METABOLIC HEALTH Société des Produits Nestlé S.A. (CH) 2026-03-04 EP claimed
EP-4701439-A1 COMPOSITIONS AND METHODS FOR IMPROVING BRAIN HEALTH Société des Produits Nestlé S.A. (CH) 2026-03-04 EP claimed
US-12404224-B2 Process for separating components of azeotropic mixtures using ionic liquids UNIVERSITY OF KANSAS (US) 2025-09-02 US claimed
WO-2025137293-A2 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. (US) 2025-06-26 WO claimed
CN-120079135-A Ionic liquid dissolvent mixture and preparation method and application thereof 浙江蓝德能源科技发展有限公司 2025-06-03 CN claimed
CN-116355015-B Preparation method of zoledronic acid 常州方圆制药有限公司 2025-04-15 CN claimed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN claimed
CN-119612552-A Preparation method of hollow Prussian blue positive electrode material 浙江山高新能源有限公司 2025-03-14 CN claimed
CN-119570482-A Bi3+、Yb3+Co-doped Cs2ZrCl6Double perovskite microcrystal and preparation method of light conversion film thereof 北京工业大学 2025-03-07 CN claimed
WO-2002102815-A2 METHODS FOR PREPARING OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHOROTHIOATE LINKAGES ISIS PHARMACEUTICALS, INC. (US) 2002-12-27 WO claimed
US-6495350-B1 AMPLIFICATION OF NUCLEIC ACID MOLECULES BY REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION; MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE, ONE OR MORE DNA POLYMERASES, AND ONE OR MORE SULFUR-CONTAINING MOLECULES INVITROGEN CORPORATION 2002-12-17 US claimed
EP-0975806-A1 COMPOSITIONS AND METHODS FOR REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (RT-PCR) Life Technologies, Inc. (US) 2000-02-02 EP claimed
WO-1998044161-A9 COMPOSITIONS AND METHODS FOR REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (RT-PCR) 1999-03-11 WO claimed
WO-1998044161-A1 COMPOSITIONS AND METHODS FOR REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (RT-PCR) LIFE TECHNOLOGIES, INC. (US) 1998-10-08 WO claimed
US-5723482-A CARNOSINE OR DERIVATIVE, UROCANIC ACID OR DERIVATIVE BEIERSDORF AG (DE) 1998-03-03 US claimed
EP-0059156-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLEACETIC-ACID DERIVATIVES SCHERING AKTIENGESELLSCHAFT (DE) 1986-04-23 EP claimed
EP-0015437-B1 METHOD AND REAGENT FOR THE DETERMINATION OF CREATINE KINASE Roche Diagnostics GmbH (DE) 1981-11-25 EP claimed
US-4286057-A QUANTITATIVE ANALYSIS OF CREATINE KINASE USING THE LUMINESCENT SYSTEM OF THE FIREFLY BOEHRINGER MANNHEIM GMBH (DE) 1981-08-25 US claimed
US-4067775-A Process and composition for determining the activity of creatinekinase-MB MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-01-10 US claimed