Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.65 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL30320112 | 1.00 | ALDH1A1 (0.65) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL28966030 | 1.00 | ALDH1A1 (0.65) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL145932 | 1.00 | — | — | |
| Imidazole SCHEMBL29188028 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL29365438 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL28213689 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL2256134 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL3639063 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL28796723 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN | |
| Imidazole SCHEMBL27735299 | 0.98 | ALDH1A1 (0.62) | ALDH1A1FKBP5FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114182259-A | Etching solution | TCL华星光电技术有限公司 | 2022-03-15 | — | — | CN | disclosed |