SCHEMBL14593265

SCHEMBL14593265

COc1cc(/N=N/c2cccc(S(=O)(=O)O)c2)ccc1Nc1nc(NCCS(=O)(=O)O)nc(Nc2ccc(/N=N/c3cc(C(=O)O)cc(C(=O)O)c3)c(C)c2)n1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 7/20 0.43
▸ PHLPP2 Q6ZVD8 1/20 0.37
▸ RAD52 P43351 1/20 0.33
▸ NCOA3 Q9Y6Q9 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ GBA1 P04062 3/20 0.33
▸ EGFR P00533 1/20 0.32
▸ IMPDH2 P12268 2/20 0.32
▸ PDE5A O76074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15958582 0.92 PHLPP2 (0.37) ENPP2PHLPP2RAD52NCOA3MEN1
SCHEMBL14593372 0.92 KMT2A (0.38) ENPP2PHLPP2MEN1KMT2AGBA1
SCHEMBL14593366 0.88 MEN1 (0.36) ENPP2PHLPP2RAD52NCOA3MEN1
SCHEMBL14593373 0.87 MEN1 (0.35) ENPP2PHLPP2MEN1KMT2AGBA1
SCHEMBL14593370 0.87 PHLPP2 (0.46) ENPP2PHLPP2IMPDH2
SCHEMBL14627084 0.85 PHLPP2 (0.39) ENPP2PHLPP2RAD52NCOA3MEN1
SCHEMBL14593416 0.84 ENPP2 (0.42) ENPP2PHLPP2IMPDH2
SCHEMBL18820790 0.81 GBA1 (0.39) PHLPP2RAD52GBA1EGFR
SCHEMBL13201661 0.81 GBA1 (0.37) PHLPP2RAD52NCOA3KMT2AGBA1
SCHEMBL14593452 0.79 PHLPP2 (0.37) ENPP2PHLPP2IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
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