SCHEMBL14593452

SCHEMBL14593452

COc1cc(Nc2nc(NCCS(=O)(=O)O)nc(Nc3ccc(/N=N/c4cc(C(=O)O)cc(C(=O)O)c4)cc3)n2)ccc1/N=N/c1cccc(P(=O)(O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 1/20 0.37
▸ ENPP2 Q13822 1/20 0.37
▸ IMPDH2 P12268 3/20 0.34
▸ KCNH3 Q9ULD8 2/20 0.32
▸ IRAK4 Q9NWZ3 1/20 0.32
▸ RHOA P61586 1/20 0.32
▸ AURKA O14965 2/20 0.32
▸ CARM1 Q86X55 1/20 0.31
▸ PRMT1 Q99873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14593416 0.94 ENPP2 (0.42) PHLPP2ENPP2IMPDH2IRAK4AURKA
SCHEMBL14627084 0.84 PHLPP2 (0.39) PHLPP2ENPP2IMPDH2AURKA
SCHEMBL14593370 0.83 PHLPP2 (0.46) PHLPP2ENPP2IMPDH2CARM1PRMT1
SCHEMBL15958582 0.80 PHLPP2 (0.37) PHLPP2ENPP2IMPDH2AURKA
SCHEMBL14593265 0.79 ENPP2 (0.43) PHLPP2ENPP2IMPDH2
SCHEMBL14593372 0.77 KMT2A (0.38) PHLPP2ENPP2RHOA
SCHEMBL13151838 0.77 CCNT1 (0.40) PHLPP2ENPP2CARM1PRMT1
SCHEMBL17813952 0.76 PHLPP2 (0.47) PHLPP2ENPP2CARM1PRMT1
SCHEMBL14593375 0.76 PHLPP2 (0.39) PHLPP2ENPP2IMPDH2RHOA
SCHEMBL14593366 0.75 MEN1 (0.36) PHLPP2ENPP2IMPDH2RHOAAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
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