SCHEMBL14593370

SCHEMBL14593370

COc1cc(Nc2nc(NCCS(=O)(=O)O)nc(Nc3ccc(/N=N/c4cc(C(=O)O)cc(C(=O)O)c4)c(C)c3)n2)ccc1/N=N/c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 2/20 0.46
▸ ENPP2 Q13822 6/20 0.44
▸ IMPDH2 P12268 3/20 0.34
▸ CA12 O43570 2/20 0.33
▸ CA1 P00915 2/20 0.33
▸ CA2 P00918 2/20 0.33
▸ CA9 Q16790 2/20 0.33
▸ CA14 Q9ULX7 2/20 0.33
▸ BRD4 O60885 2/20 0.33
▸ CARM1 Q86X55 1/20 0.32
▸ PRMT1 Q99873 1/20 0.32
▸ RPS6KA3 P51812 1/20 0.32
▸ AMY1A P0DUB6 1/20 0.32
▸ FLT3 P36888 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14593265 0.87 ENPP2 (0.43) PHLPP2ENPP2IMPDH2
SCHEMBL14593416 0.86 ENPP2 (0.42) PHLPP2ENPP2IMPDH2
SCHEMBL14593372 0.85 KMT2A (0.38) PHLPP2ENPP2CA12CA1CA2
SCHEMBL17813952 0.84 PHLPP2 (0.47) PHLPP2ENPP2CA12CA1CA2
SCHEMBL14627084 0.84 PHLPP2 (0.39) PHLPP2ENPP2IMPDH2
SCHEMBL14593452 0.83 PHLPP2 (0.37) PHLPP2ENPP2IMPDH2CARM1PRMT1
SCHEMBL6125349 0.82 CD40 (0.45) PHLPP2ENPP2CA12CA1CA2
SCHEMBL14593373 0.81 MEN1 (0.35) PHLPP2ENPP2CA12CA1CA2
SCHEMBL17814006 0.81 CD40 (0.44) PHLPP2ENPP2CA12CA1CA2
SCHEMBL14593451 0.81 SENP2 (0.48) PHLPP2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
US-7163576-B2 to improve the light-fastness properties of prints is to prevent images fading or vanishing, or becoming discoloured over time FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-01-16 — — US disclosed
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