Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593442 | 0.90 | MEN1 (0.50) | MC4RKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL14593418 | 0.90 | MC4R (0.60) | MC4RGPR119GLS | |
| SCHEMBL14593313 | 0.89 | ALDH1A1 (0.49) | MC4RGPR119SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL14593413 | 0.87 | MC4R (0.48) | MC4RGPR119KMT2AMEN1MAPT | |
| SCHEMBL14593321 | 0.86 | MC4R (0.55) | MC4RGPR119KMT2AMEN1GLS | |
| SCHEMBL14593336 | 0.83 | GPR119 (0.48) | GPR119KMT2AMEN1CYP2C19SMN1; SMN2 | |
| SCHEMBL5411667 | 0.81 | MC4R (0.48) | MC4RGPR119KMT2AMEN1GLS | |
| SCHEMBL14593457 | 0.80 | MC4R (0.67) | MC4RALDH1A1MAPTGLS | |
| SCHEMBL14593374 | 0.80 | MC4R (0.62) | MC4RGPR119ALDH1A1GLSKDM1A | |
| SCHEMBL14593448 | 0.79 | MC4R (0.65) | MC4RKMT2AMEN1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |