Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 16/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160418 | 0.76 | CLK4 (0.41) | CLK4DYRK1ACLK1KDM4EALDH1A1 | |
| SCHEMBL2586735 | 0.71 | ADRB2 (0.47) | CLK4DYRK1ACLK1KDM4EALDH1A1 | |
| Succinic Acid SCHEMBL2587865 | 0.71 | ALDH1A1 (0.38) | CLK4DYRK1ACLK1KDM4EALDH1A1 | |
| SCHEMBL13685572 | 0.69 | CLK4 (0.34) | CLK4DYRK1ACLK1KDM4EALDH1A1 | |
| SCHEMBL2579999 | 0.67 | ACACB (0.48) | CLK4CLK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11948255 | 0.66 | MAOA (0.31) | — | |
| SCHEMBL14488434 | 0.64 | CLK4 (0.49) | CLK4DYRK1ACLK1ALDH1A1CYP1A2 | |
| SCHEMBL2588748 | 0.63 | GNRHR (0.46) | — | |
| SCHEMBL11948250 | 0.62 | — | — | |
| SCHEMBL13825303 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |