SCHEMBL14595486

SCHEMBL14595486

Cc1ccc(-c2ccc(-c3cc(C)cc(C)c3)s2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 8/20 0.63
HSD17B2 P37059 8/20 0.63
APP P05067 7/20 0.50
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2E1 P05181 1/20 0.43
CYP2C8 P10632 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP4B1 P13584 1/20 0.43
CYP2B6 P20813 1/20 0.43
CYP3A5 P20815 1/20 0.43
CYP2A7 P20853 1/20 0.43
CYP3A7 P24462 1/20 0.43
CYP2F1 P24903 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968693 0.88 APP (0.55) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL12575567 0.85 APP (0.52) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL12973225 0.82 APP (0.77) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL14179953 0.82 HSD17B1 (0.54) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL12918733 0.79 CYP1A1 (0.48) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL10154028 0.79 HSD17B1 (0.50) HSD17B1HSD17B2APPCYP3A4CYP2D6
SCHEMBL6015219 0.79 RXFP1 (0.53) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL12307014 0.79 APP (0.46) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL1180575 0.78 HSD17B1 (1.00) HSD17B1HSD17B2APPESR1ESR2
SCHEMBL10016215 0.77 APP (0.45) HSD17B1HSD17B2APPESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070009760-A1 Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device INOUE TETSUYA 2007-01-11 US disclosed