Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16440498 | 0.95 | HSD17B1 (0.50) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL12887829 | 0.87 | ERN1 (0.46) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL12887840 | 0.83 | CYP3A4 (0.46) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL147294 | 0.80 | HSD17B1 (0.49) | HSD17B1HSD17B2PGRNPC1ALDH1A1 | |
| SCHEMBL9927249 | 0.79 | APP (0.48) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL18677167 | 0.79 | PGR (0.45) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL17149181 | 0.79 | ERN1 (0.41) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL14595486 | 0.79 | HSD17B1 (0.63) | HSD17B1HSD17B2MAPTCYP1A1CYP1A2 | |
| SCHEMBL24341916 | 0.79 | CYP2A6 (0.50) | HSD17B1HSD17B2ERN1PGRNPC1 | |
| SCHEMBL12404008 | 0.78 | HSD17B1 (0.38) | HSD17B1HSD17B2ERN1PGRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423192-A1 | METAL COMPLEX HAVING AROMATIC LIGAND THAT CONTAINS NITROGEN ATOM | Sumitomo Chemical Company, Limited (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8008507-B2 | Fluorescent diketopyrrolopyrroles | BASF SE Ludwigshafen (DE) | 2011-08-30 | — | — | US | disclosed |
| US-8008507-B2 | Fluorescent diketopyrrolopyrroles | BASF SE Ludwigshafen (DE) | 2011-08-30 | — | — | US | disclosed |
| US-7906039-B2 | Fluorescent diketopyrrolopyrroles | BASF SE (DE) | 2011-03-15 | — | — | US | disclosed |
| US-7906039-B2 | Fluorescent diketopyrrolopyrroles | BASF SE (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090173916-A1 | Fluorescent diketopyrrolopyrroles | CLAP CO., LTD. (KR) | 2009-07-09 | — | — | US | disclosed |
| US-20090173916-A1 | Fluorescent diketopyrrolopyrroles | CLAP CO., LTD. (KR) | 2009-07-09 | — | — | US | disclosed |
| US-7501076-B2 | Fluorescent diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501076-B2 | Fluorescent diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-03-10 | — | — | US | disclosed |
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2009-03-05 | — | — | US | disclosed |
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2009-03-05 | — | — | US | disclosed |
| EP-1817392-B1 | FLUORESCENT DIKETOPYRROLOPYRROLES | CIBA HOLDING INC (CH) | 2009-01-07 | — | — | EP | disclosed |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | CIBA CORPORATION | 2008-09-11 | — | — | US | disclosed |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | CIBA CORPORATION | 2008-09-11 | — | — | US | disclosed |
| US-20070010672-A1 | Fluorescent diketopyrrolopyrroles | CLAP CO., LTD. (KR) | 2007-01-11 | — | — | US | disclosed |
| US-20070010672-A1 | Fluorescent diketopyrrolopyrroles | CLAP CO., LTD. (KR) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | HSD17B1 3779/4885HSD17B2 3637/4885ERN1 3401/4885 |
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | TYR, IK, MC1R | HSD17B1 3396/4885HSD17B2 4286/4885ERN1 4793/4885 |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | TYR, MC1R, IK | HSD17B1 3659/4885HSD17B2 4007/4885ERN1 3197/4885 |
| US-20070010672-A1 | Fluorescent diketopyrrolopyrroles | TYR, QDPR, MC1R | HSD17B1 3419/4885HSD17B2 3929/4885ERN1 4267/4885 |
| US-20090173916-A1 | Fluorescent diketopyrrolopyrroles | TYR, IK, MC1R | HSD17B1 3536/4885HSD17B2 4156/4885ERN1 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.