Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354991 | 0.77 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL354990 | 0.77 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL13738165 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL15761142 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL13738168 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL25254802 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL17133880 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL4812007 | 0.73 | ALDH1A1 (0.46) | LMNAHPGDL3MBTL1MAPTKDM4E | |
| SCHEMBL30409328 | 0.73 | LMNA (0.49) | LMNAHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL14445625 | 0.72 | LMNA (0.45) | LMNAHSD17B10HPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | OGG1, CBR3, C1R | LMNA 1220/4885HSD17B10 1660/4885HPGD 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.