Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484008 | 0.83 | TDP1 (0.40) | MAPTALDH1A1L3MBTL1CYP3A4TDP1 | |
| SCHEMBL6842001 | 0.82 | MAPT (0.45) | MAPTALDH1A1L3MBTL1HTTTDP1 | |
| SCHEMBL11518218 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9452414 | 0.76 | MAPT (0.61) | MAPTALDH1A1L3MBTL1CYP3A4HTT | |
| SCHEMBL14596287 | 0.75 | SMN1; SMN2 (0.58) | MAPTALDH1A1CYP2D6RAB9ATSHR | |
| SCHEMBL4315388 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1HTTTDP1MEN1 | |
| SCHEMBL180817 | 0.73 | APP (0.55) | MAPTALDH1A1L3MBTL1CYP3A4HTT | |
| SCHEMBL6318640 | 0.73 | HRH3 (0.46) | MAPTALDH1A1CYP3A4HTTCYP1A2 | |
| SCHEMBL5157848 | 0.73 | APP (0.44) | MAPTALDH1A1L3MBTL1CYP3A4HTT | |
| SCHEMBL5692969 | 0.72 | PRSS1 (0.39) | MAPTALDH1A1L3MBTL1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739079-A1 | Novel bis-para-phenylendiamins joined by a linker arm comprising a sulphur or nitrogen atom and their use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | KRT18, DSP, CDC73 | MAPT 2521/4885ALDH1A1 798/4885L3MBTL1 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.