SCHEMBL484008

SCHEMBL484008

Nc1ccc(NCCN(CCO)c2ccc(N)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
PSMD14 O00487 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
GFER P55789 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
APP P05067 1/20 0.38
MAPT P10636 3/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
HRH3 Q9Y5N1 1/20 0.34
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692969 0.89 PRSS1 (0.39) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL855272 0.89 PRSS1 (0.39) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL4668959 0.86 ALDH1A1 (0.42) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL9490421 0.84 ALDH1A1 (0.43) TDP1ALDH1A1TSHRMAPTKMT2A
SCHEMBL9022771 0.84 ALDH1A1 (0.53) TDP1ALDH1A1TSHRMAPK1RECQL
SCHEMBL2988963 0.84 CNR2 (0.48) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL8521178 0.84 ALDH1A1 (0.54) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL28087334 0.84 ALDH1A1 (0.54) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL33874 0.84 ALDH1A1 (0.54) TDP1ALDH1A1TSHRPSMD14CYP3A4
SCHEMBL14596282 0.83 MAPT (0.44) TDP1ALDH1A1TSHRPSMD14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047376-B1 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME OREAL (FR) 2001-05-23 EP claimed
US-5609649-A Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them L'OREAL (FR) 1997-03-11 US claimed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP claimed
CN-120035427-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-23 CN disclosed
CN-119968189-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-09 CN disclosed
CN-119894486-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-25 CN disclosed
CN-119855579-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-18 CN disclosed
CN-119836282-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-15 CN disclosed
CN-118488824-A Compositions, methods and kits for altering hair color 欧莱雅 2024-08-13 CN disclosed
CN-118401231-A Composition for keratin fibres 莱雅公司 2024-07-26 CN disclosed
CN-117715615-A Composition comprising at least one oxidation dye, 1, 3-propanediol, at least one alkaline agent and at least one fatty substance 莱雅公司 2024-03-15 CN disclosed
CN-114340739-A Composition for dyeing keratin fibres 莱雅公司 2022-04-12 CN disclosed
CN-105828884-B Packaging article comprising an envelope and an anhydrous dye composition comprising an oxidation dye, use thereof and process for dyeing keratin fibres 莱雅公司 2022-04-08 CN disclosed
CN-114286712-A Composition for dyeing keratin fibres 莱雅公司 2022-04-05 CN disclosed
CN-114269320-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-01 CN disclosed
CN-108472232-B Composition for dyeing hair comprising an oxidation base of the p-phenylenediamine type and a coupler of 2-amino-5-ethylphenol 莱雅公司 2022-02-18 CN disclosed
US-20130042882-A1 COLORANTS FOR KERATINIC FIBRES HAVING OPTIMIZED VISCOSITY ADJUSTMENT HENKEL AG & CO. KGAA (DE) 2013-02-21 US disclosed
EP-2010494-B1 SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES OREAL (FR) 2012-02-01 EP disclosed
US-6383231-B1 MIXTURE CONTAINING ANIONIC SURFACTANT L'OREAL (FR) 2002-05-07 US disclosed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US disclosed