Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596375 | 0.83 | MLYCD (0.40) | EPHX2NR1H4ALDH1A1MLYCDHPGD | |
| SCHEMBL4785358 | 0.79 | ALDH1A1 (0.57) | EPHX2NR1H4ALDH1A1HPGDNPSR1 | |
| SCHEMBL23190817 | 0.79 | HDAC3 (0.49) | EPHX2MLYCDHPGDNPSR1KMT2A | |
| SCHEMBL10050990 | 0.78 | EPHX2 (0.58) | EPHX2NR1H4ALDH1A1HPGDKMT2A | |
| SCHEMBL1663138 | 0.77 | ALDH1A1 (0.49) | EPHX2NR1H4ALDH1A1MLYCDHPGD | |
| SCHEMBL2647552 | 0.77 | EPHX2 (0.48) | EPHX2NR1H4ALDH1A1MLYCDHPGD | |
| SCHEMBL19117102 | 0.77 | SMN1; SMN2 (0.63) | EPHX2NR1H4ALDH1A1HPGDKMT2A | |
| SCHEMBL2647548 | 0.77 | EPHX2 (0.48) | EPHX2NR1H4ALDH1A1MLYCDHPGD | |
| SCHEMBL2647795 | 0.77 | ALDH1A1 (0.54) | EPHX2NR1H4ALDH1A1MLYCDHPGD | |
| SCHEMBL2647793 | 0.77 | ALDH1A1 (0.54) | EPHX2NR1H4ALDH1A1MLYCDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | GLP1R, GCGR, GIPR | EPHX2 3617/4885NR1H4 127/4885ALDH1A1 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.