Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23106513 | 0.86 | MLYCD (0.61) | HDAC3HDAC1HDAC2MLYCDHPGD | |
| SCHEMBL6978532 | 0.85 | NAMPT (0.56) | HDAC3HDAC1HDAC2MLYCDHPGD | |
| SCHEMBL6975861 | 0.85 | NAMPT (0.56) | HDAC3HDAC1HDAC2MLYCDHPGD | |
| SCHEMBL14596376 | 0.79 | EPHX2 (0.51) | MLYCDHPGDNPSR1EPHX2KMT2A | |
| SCHEMBL14265187 | 0.77 | HDAC3 (0.53) | HDAC3HDAC1HDAC2EPHX2KMT2A | |
| SCHEMBL13753745 | 0.77 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HPGDKMT2A | |
| SCHEMBL14265188 | 0.75 | HDAC3 (0.61) | HDAC3HDAC1HDAC2KMT2AHTT | |
| SCHEMBL17865783 | 0.74 | MLYCD (0.73) | MLYCDHPGDNPSR1EPHX2KMT2A | |
| SCHEMBL14075729 | 0.74 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HPGDNPSR1 | |
| SCHEMBL6975868 | 0.74 | HDAC3 (0.60) | HDAC3HDAC1HDAC2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019615-B1 | CYSTOBACTAMIDES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |