Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437561 | 0.92 | PTGDR (0.33) | PTGDRPTGDR2SYKEPHX2ALDH1A1 | |
| SCHEMBL12748354 | 0.89 | KMT2A (0.34) | SYKALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1464150 | 0.89 | THRA (0.33) | PTGDR2SYKSLC13A5 | |
| SCHEMBL1464148 | 0.89 | THRA (0.33) | PTGDR2SYKSLC13A5 | |
| SCHEMBL3437747 | 0.89 | THRA (0.33) | PTGDR2SYKSLC13A5 | |
| SCHEMBL12827205 | 0.85 | KMT2A (0.36) | SYKALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4697247 | 0.85 | KMT2A (0.36) | SYKALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12748374 | 0.85 | SYK (0.32) | SYKACKR3 | |
| SCHEMBL1465423 | 0.85 | SYK (0.32) | SYKACKR3 | |
| SCHEMBL7999874 | 0.70 | NPC1 (0.40) | EPHX2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023381-A1 | METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS | PFIZER INC. (US) | 2007-03-01 | — | — | WO | disclosed |