Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827205 | 1.00 | KMT2A (0.36) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL3437561 | 0.91 | PTGDR (0.33) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL12748354 | 0.91 | KMT2A (0.34) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL12748374 | 0.87 | SYK (0.32) | SYK | |
| SCHEMBL14596706 | 0.85 | PTGDR (0.35) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3437747 | 0.84 | THRA (0.33) | SYK | |
| SCHEMBL1464148 | 0.84 | THRA (0.33) | SYK | |
| SCHEMBL12344015 | 0.73 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12341148 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL13964139 | 0.73 | RAB9A (0.40) | KMT2AMEN1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928878-A1 | METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS | PFIZER INC. (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007023381-A1 | METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS | PFIZER INC. (US) | 2007-03-01 | — | — | WO | disclosed |