SCHEMBL14599088

SCHEMBL14599088

COC(=O)CN(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(C)=O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.69
PPARA Q07869 16/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13721310 0.92 PPARG (0.68) PPARGPPARA
SCHEMBL14599083 0.92 PPARA (0.79) PPARGPPARA
SCHEMBL6342308 0.89 PPARA (0.87) PPARGPPARA
SCHEMBL13721845 0.84 PPARA (0.79) PPARGPPARA
SCHEMBL13721541 0.84 PPARA (0.67) PPARGPPARA
SCHEMBL7906850 0.83 PPARG (0.69) PPARGPPARA
SCHEMBL5451604 0.83 PPARG (0.96) PPARGPPARA
SCHEMBL13721298 0.82 PPARG (0.69) PPARGPPARA
SCHEMBL14360184 0.82 PPARG (0.79) PPARGPPARA
SCHEMBL13722007 0.82 PPARG (0.69) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method CHENG PETER T 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method GPR119, LIPC, ACACA PPARG 65/4885PPARA 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.