Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6740203 | 0.98 | KCNH2 (0.53) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL5175466 | 0.86 | KCNH2 (0.45) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL692248 | 0.84 | IMPDH2 (0.54) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL34467254 | 0.83 | KCNH2 (0.57) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| Hydrochloric Acid SCHEMBL456649 | 0.82 | IMPDH2 (0.53) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL1378848 | 0.81 | PELI1 (0.54) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL6255907 | 0.81 | PELI1 (0.53) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL18516478 | 0.81 | KCNH2 (0.52) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| SCHEMBL27684579 | 0.81 | KCNH2 (0.52) | KCNH2IMPDH2CYP2A6TDO2MAPT | |
| Hydrochloric Acid SCHEMBL6287793 | 0.79 | PELI1 (0.53) | KCNH2IMPDH2CYP2A6TDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| CN-100549003-C | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2009-10-14 | — | — | CN | claimed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| EP-1670423-B1 | DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | claimed |
| CN-100358887-C | m-aminophenol derivatives and dyes containing these compounds | P & G CLAIROL INC (US) | 2008-01-02 | — | — | CN | claimed |
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-22 | — | — | US | claimed |
| US-6503282-B1 | Composition for coloring keratin fibers based on a developer-coupler combination characterized in that it contains as the coupler 3-(2,4-diaminophenoxy)-1-propanol and as the developer ring and having general formula (I) | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-07 | — | — | US | claimed |
| US-6409773-B1 | AMINOPHENOL COUPLERS | CLAIROL INCORPORATED | 2002-06-25 | — | — | US | claimed |
| WO-2002047635-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2002-06-20 | — | — | WO | claimed |
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | claimed |
| EP-1166749-A2 | Composition and process for dyeing keratinic fibres | Wella Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | claimed |
| EP-1158954-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | Wella Aktiengesellschaft (DE) | 2001-12-05 | — | — | EP | claimed |
| WO-2001051019-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | claimed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | claimed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | KCNH2 2187/4885IMPDH2 1520/4885CYP2A6 659/4885 |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | KCNH2 1851/4885IMPDH2 2760/4885CYP2A6 288/4885 |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | KRT18, DSP, TUBB4B | KCNH2 615/4885IMPDH2 3411/4885CYP2A6 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.