Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567017 | 1.00 | GRM5 (0.46) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL5567321 | 0.71 | GRM5 (0.46) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL15494395 | 0.71 | GRM5 (0.53) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3353813 | 0.67 | GRM5 (0.68) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL729985 | 0.67 | KMT2A (0.38) | GRM5 | |
| SCHEMBL14006347 | 0.66 | — | — | |
| SCHEMBL12230330 | 0.65 | GRM5 (0.32) | GRM5 | |
| SCHEMBL8024334 | 0.65 | GRM5 (0.32) | GRM5 | |
| SCHEMBL8024330 | 0.65 | GRM5 (0.32) | GRM5 | |
| SCHEMBL14587140 | 0.65 | GRM5 (0.32) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157595-B2 | Degradation of epothilones | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2007-01-02 | — | — | US | disclosed |