Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15483095 | 0.74 | GRM5 (0.53) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL102265 | 0.72 | GRM5 (0.60) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL14599876 | 0.71 | GRM5 (0.46) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL102176 | 0.68 | GRM5 (0.49) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL28749297 | 0.67 | — | — | |
| SCHEMBL14629798 | 0.67 | PKM (0.43) | — | |
| SCHEMBL22894216 | 0.67 | GRM5 (0.51) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL103069 | 0.65 | HPGD (0.46) | GRM5 | |
| SCHEMBL22692446 | 0.65 | HIF1A (0.34) | — | |
| SCHEMBL102610 | 0.65 | NPC1 (0.50) | GRM5CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157595-B2 | Degradation of epothilones | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2007-01-02 | — | — | US | disclosed |
| EP-1564217-B1 | Process for the production of epothilones | BIOTECHNOLOG FORSCHUNG GMBH (DE) | 2006-08-09 | — | — | EP | disclosed |
| EP-1564217-A2 | Process for the production of epothilones | Gesellschaft für biotechnologische Forschung mbH (GBF) (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20040092560-A1 | Degradation of epothilones | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092560-A1 | Degradation of epothilones | DHPS, OTUB1, FTO | GRM5 3749/4885CYP1A2 83/4885CYP2D6 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.