Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KLK8 | O60259 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLK2 | P20151 | 1/20 | 0.40 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945294 | 0.87 | ANPEP (0.44) | ANPEPLAP3L3MBTL1ALDH1A1CA12 | |
| SCHEMBL10626029 | 0.83 | SRC (0.52) | ANPEPLAP3L3MBTL1SRCKLK8 | |
| SCHEMBL5945293 | 0.81 | CCNT1 (0.48) | ANPEPLAP3L3MBTL1ALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL10623947 | 0.81 | SRC (0.50) | ANPEPLAP3L3MBTL1SRCKLK8 | |
| Bromide SCHEMBL10905594 | 0.81 | SRC (0.50) | ANPEPLAP3L3MBTL1SRCKLK8 | |
| SCHEMBL1028971 | 0.76 | L3MBTL1 (0.53) | ANPEPLAP3L3MBTL1ALDH1A1CA12 | |
| SCHEMBL2535071 | 0.76 | L3MBTL1 (0.53) | ANPEPLAP3L3MBTL1ALDH1A1CA12 | |
| SCHEMBL10739177 | 0.74 | CTSA (0.43) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL14269491 | 0.74 | ANPEP (0.42) | ANPEPLAP3L3MBTL1ALDH1A1CA12 | |
| SCHEMBL9485312 | 0.74 | BTN3A1 (0.41) | ANPEPLAP3L3MBTL1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | ANPEP 24/4885LAP3 222/4885L3MBTL1 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.