Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.48 |
| ▸ | CDK9 | P50750 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454035 | 0.86 | L3MBTL1 (0.53) | L3MBTL1PRTN3MEN1KMT2A | |
| SCHEMBL5945294 | 0.85 | ANPEP (0.44) | CCNT1CDK9L3MBTL1ALDH1A1ANPEP | |
| SCHEMBL14600552 | 0.81 | ANPEP (0.46) | L3MBTL1ALDH1A1ANPEPLAP3MEN1 | |
| SCHEMBL5945612 | 0.81 | BTN3A1 (0.45) | L3MBTL1ALDH1A1PRTN3ANPEPLAP3 | |
| SCHEMBL5945483 | 0.81 | BTN3A1 (0.45) | L3MBTL1ALDH1A1PRTN3ANPEPLAP3 | |
| SCHEMBL5945489 | 0.81 | BTN3A1 (0.45) | L3MBTL1ALDH1A1PRTN3ANPEPLAP3 | |
| SCHEMBL9485312 | 0.79 | BTN3A1 (0.41) | CCNT1CDK9L3MBTL1ALDH1A1ANPEP | |
| SCHEMBL649001 | 0.78 | MEN1 (0.51) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7739962 | 0.75 | CTSA (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL4456003 | 0.75 | L3MBTL1 (0.50) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172295-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8431745-B2 | Process for preparation of HIV protease inhibitors | GILEAD SCIENCES, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120258935-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHBITORS | GILEAD SCIENCES, INC. (US) | 2012-10-11 | — | — | US | disclosed |
| US-8173623-B2 | Process for preparation of HIV protease inhibitors | GILEAD SCIENCES, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110065631-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC (US) | 2011-03-17 | — | — | US | disclosed |
| US-20080004242-A1 | Process for preparation of HIV protease inhibitors | GILEAD SCIENCES, INC. | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172295-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | PRSS1, PREP, SERPINB1 | CCNT1 517/4885CDK9 352/4885L3MBTL1 3523/4885 |
| US-20120258935-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHBITORS | PREP, FURIN, PRSS1 | CCNT1 916/4885CDK9 715/4885L3MBTL1 3677/4885 |
| US-20110065631-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | PREP, PRSS1, SERPINB1 | CCNT1 410/4885CDK9 204/4885L3MBTL1 3993/4885 |
| US-20080004242-A1 | Process for preparation of HIV protease inhibitors | PRSS1, PREP, SERPINB1 | CCNT1 517/4885CDK9 352/4885L3MBTL1 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.