Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665548 | 0.90 | ALDH1A1 (0.43) | MARS1KMT2AMEN1MAPK14SPR | |
| SCHEMBL6353421 | 0.85 | MEN1 (0.41) | KMT2AMEN1DHODHMAPK14KDM4E | |
| SCHEMBL6342666 | 0.81 | OXTR (0.51) | MARS1KMT2AMEN1ADORA1DHODH | |
| SCHEMBL6343631 | 0.76 | MEN1 (0.52) | KMT2AMEN1ADORA1DHODHALDH1A1 | |
| SCHEMBL6344686 | 0.75 | KMT2A (0.53) | KMT2AMEN1MAPK14ALDH1A1 | |
| SCHEMBL6345124 | 0.75 | MEN1 (0.56) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL6340206 | 0.74 | GFER (0.62) | KMT2AMEN1SPRKDM4EALDH1A1 | |
| SCHEMBL4664691 | 0.74 | ADORA1 (0.43) | KMT2AMEN1ADORA1DHODH | |
| SCHEMBL6339758 | 0.73 | MAPT (0.64) | KMT2AMEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9880025 | 0.73 | ALDH1A1 (0.53) | MARS1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |