Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19403881 | 0.85 | MEN1 (0.45) | HPGDGAARAB9AKMT2AMMP13 | |
| SCHEMBL9796560 | 0.82 | HPGD (0.44) | HPGDNPSR1GAARAB9AKMT2A | |
| SCHEMBL16421199 | 0.82 | CLCN2 (0.53) | HPGDGAAKMT2AHSD17B10MEN1 | |
| SCHEMBL22067720 | 0.81 | KDM4E (0.51) | HPGDGAARAB9AKMT2ALMNA | |
| SCHEMBL328219 | 0.80 | SMN1; SMN2 (0.56) | RAB9AKMT2AMMP13SMN1; SMN2NPC1 | |
| SCHEMBL5498242 | 0.80 | MEN1 (0.59) | HPGDNPSR1GAARAB9AKMT2A | |
| SCHEMBL22066857 | 0.80 | SMN1; SMN2 (0.49) | HPGDRAB9AKMT2ALMNAMMP13 | |
| SCHEMBL22957967 | 0.79 | KDM4E (0.59) | HPGDGAALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL3811074 | 0.79 | KDM4E (0.54) | NPSR1GAARAB9AKMT2AKCNMA1 | |
| SCHEMBL20418534 | 0.78 | TAS1R3 (0.55) | RAB9ALMNATSHRHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |