Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796166 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL1321725 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL3787454 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAGAAALOX15 | |
| SCHEMBL23466539 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1ALOX15PYGLKMT2A | |
| SCHEMBL7169725 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL4154496 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1GAAALOX15PYGL | |
| SCHEMBL29833777 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1GAAALOX15PYGL | |
| SCHEMBL5875315 | 0.80 | ABL1 (0.62) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL8318320 | 0.79 | FLT1 (0.59) | KDM4EALDH1A1ALOX15PYGLKMT2A | |
| SCHEMBL14601264 | 0.79 | HPGD (0.43) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-7524855-B2 | Selected benzofuran derivatives | ARPIDA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20080108610-A1 | Selected Benzofuran Derivatives | ARPIDA AG (CH) | 2008-05-08 | — | — | US | disclosed |
| CN-101087779-A | Selected benzofuran derivatives | ARPIDA AG (CH) | 2007-12-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108610-A1 | Selected Benzofuran Derivatives | ABCG2, BPTF, SBDS | KDM4E 1756/4885ALDH1A1 972/4885GLA 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.