Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 6/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.62 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760372 | 1.00 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11760343 | 0.99 | TIMP3 (0.63) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11761517 | 0.93 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14107312 | 0.93 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14601341 | 0.93 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11761453 | 0.92 | TIMP3 (0.63) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14640094 | 0.91 | NT5E (0.61) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11582873 | 0.89 | PRMT1 (0.63) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11582847 | 0.88 | PRMT1 (0.62) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11495430 | 0.88 | PRMT1 (0.62) | TIMP3RECQLKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | CD2BP2, MASP2, CD14 | TIMP3 1675/4885RECQL 4113/4885KMT2A 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.