Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MMP2 | P08253 | 7/20 | 0.55 |
| ▸ | MMP3 | P08254 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450219 | 0.95 | ALDH1A1 (0.50) | ALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL91873 | 0.87 | MMP2 (0.57) | ALDH1A1HPGDMMP2MMP3KDM4E | |
| SCHEMBL21386579 | 0.87 | MMP2 (0.57) | ALDH1A1HPGDMMP2MMP3KDM4E | |
| SCHEMBL9146899 | 0.87 | MMP2 (0.57) | ALDH1A1HPGDMMP2MMP3KDM4E | |
| SCHEMBL11523891 | 0.83 | GRIA1 (0.44) | ALDH1A1HPGDMMP2MMP3HRH3 | |
| SCHEMBL11523895 | 0.83 | GRIA1 (0.44) | ALDH1A1HPGDMMP2MMP3HRH3 | |
| SCHEMBL3274920 | 0.83 | MMP2 (0.59) | ALDH1A1HPGDMMP2MMP3KDM4E | |
| SCHEMBL3274914 | 0.83 | MMP2 (0.59) | ALDH1A1HPGDMMP2MMP3KDM4E | |
| SCHEMBL8436281 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDMMP2MMP3HRH3 | |
| SCHEMBL18979622 | 0.82 | MMP2 (0.50) | ALDH1A1HPGDMMP2MMP3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166337-B2 | Liquid-crystal composition, methods of adjusting the resistance, and substituted phenols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-01-23 | — | — | US | disclosed |
| US-7166337-B2 | Liquid-crystal composition, methods of adjusting the resistance, and substituted phenols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-01-23 | — | — | US | disclosed |