Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.59 |
| ▸ | MMP3 | P08254 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274920 | 1.00 | MMP2 (0.59) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL3274873 | 0.90 | MMP2 (0.51) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL3274876 | 0.90 | MMP2 (0.51) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL3275041 | 0.87 | MMP2 (0.54) | MMP2MMP3ALDH1A1HPGDMAPT | |
| SCHEMBL3275036 | 0.87 | MMP2 (0.54) | MMP2MMP3ALDH1A1HPGDMAPT | |
| SCHEMBL9146899 | 0.85 | MMP2 (0.57) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL21386579 | 0.85 | MMP2 (0.57) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL91873 | 0.85 | MMP2 (0.57) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL10708127 | 0.83 | ALDH1A1 (0.66) | MMP2MMP3ALDH1A1HPGDKDM4E | |
| SCHEMBL9924742 | 0.83 | MMP2 (0.61) | MMP2MMP3ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562863-B2 | Cholesteric glassy liquid crystals with hybrid chiral-nematic mesogens | THE UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |
| US-20100086704-A1 | CHOLESTERIC GLASSY LIQUID CRYSTALS WITH HYBRID CHIRAL-NEMATIC MESOGENS | THE UNIVERSITY OF ROCHESTER | 2010-04-08 | — | — | US | disclosed |