SCHEMBL14601465

SCHEMBL14601465

C#COCc1cc(C)c(O)c(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.41
MET P08581 2/20 0.38
TNKS2 Q9H2K2 2/20 0.38
AKR1B1 P15121 1/20 0.37
TNKS O95271 1/20 0.37
GAA P10253 2/20 0.36
ALOX5 P09917 4/20 0.36
PTGS2 P35354 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TUBB4A P04350 2/20 0.35
TUBB P07437 2/20 0.35
TUBA3C P0DPH7 2/20 0.35
TUBA1B P68363 2/20 0.35
TUBA4A P68366 2/20 0.35
TUBB4B P68371 2/20 0.35
TUBB3 Q13509 2/20 0.35
TUBB2A Q13885 2/20 0.35
TUBB8 Q3ZCM7 2/20 0.35
TUBA3E Q6PEY2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28499293 0.81 ERN1 (0.44) EGFRMETTNKS2AKR1B1TNKS
SCHEMBL9620471 0.77 SHBG (0.52) EGFRTNKS2AKR1B1TNKSGAA
SCHEMBL14262143 0.76 TNKS2 (0.47) EGFRMETTNKS2AKR1B1TNKS
SCHEMBL12121960 0.75 PTGS2 (0.55) EGFRTNKS2AKR1B1TNKSGAA
SCHEMBL12510599 0.75 TNKS2 (0.49) EGFRTNKS2AKR1B1TNKSGAA
SCHEMBL16362239 0.75 AKR1B1 (0.61) EGFRMETTNKS2AKR1B1TNKS
SCHEMBL27873502 0.74 TAAR1 (0.44) EGFRTNKS2AKR1B1TNKSGAA
SCHEMBL10986051 0.73 TNKS2 (0.50) EGFRTNKS2AKR1B1ALOX5PTGS2
SCHEMBL10293953 0.71 TNKS (0.67) TNKS2TNKSGAAALOX5MAPT
SCHEMBL6306425 0.71 MAPT (0.62) EGFRTNKS2AKR1B1TNKSGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160645-B2 Lead-acid battery having an organic polymer additive and process thereof KOZAWA AKIYA 2007-01-09 US disclosed