SCHEMBL28499293

SCHEMBL28499293

COCc1cc(C)c(O)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.44
TNKS2 Q9H2K2 2/20 0.43
MET P08581 1/20 0.43
EGFR P00533 1/20 0.42
AKR1B1 P15121 1/20 0.42
TNKS O95271 1/20 0.41
ALOX5 P09917 3/20 0.41
PTGS2 P35354 1/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
TUBB4A P04350 2/20 0.39
TUBB P07437 2/20 0.39
TUBA3C P0DPH7 2/20 0.39
TUBA1B P68363 2/20 0.39
TUBA4A P68366 2/20 0.39
TUBB4B P68371 2/20 0.39
TUBB3 Q13509 2/20 0.39
TUBB2A Q13885 2/20 0.39
TUBB8 Q3ZCM7 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28325906 0.88 AKR1B1 (0.52) ERN1TNKS2METAKR1B1ALOX5
SCHEMBL9191718 0.86 CA1 (0.46) ERN1ALOX5PTGS2GAAMAPT
SCHEMBL9620471 0.84 SHBG (0.52) TNKS2EGFRAKR1B1TNKSALOX5
SCHEMBL16362239 0.82 AKR1B1 (0.61) TNKS2METEGFRAKR1B1TNKS
SCHEMBL12121960 0.82 PTGS2 (0.55) TNKS2EGFRAKR1B1TNKSALOX5
SCHEMBL12510599 0.82 TNKS2 (0.49) ERN1TNKS2EGFRAKR1B1TNKS
SCHEMBL14601465 0.81 EGFR (0.41) TNKS2METEGFRAKR1B1TNKS
SCHEMBL27873502 0.81 TAAR1 (0.44) TNKS2EGFRAKR1B1TNKSALOX5
SCHEMBL16854091 0.80 SHBG (0.52) ERN1PTGS2MAPTALDH1A1PTGS1
SCHEMBL14262143 0.79 TNKS2 (0.47) ERN1TNKS2METEGFRAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079697-A Preparation method of 5-methyl vanillin 上海应用技术大学 2020-12-15 CN disclosed