Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601557 | 0.87 | PDE4A (0.44) | NPSR1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL5166787 | 0.85 | MAPT (0.62) | NPSR1MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL5166792 | 0.85 | MAPT (0.62) | NPSR1MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL14601555 | 0.81 | MAPT (0.51) | MAPTLMNAALDH1A1PDE4APDE4B | |
| SCHEMBL14601554 | 0.80 | MAPT (0.48) | NPSR1MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL10764854 | 0.78 | PDE4A (0.60) | TSHRMAPTLMNAPDE4APDE4B | |
| SCHEMBL10764858 | 0.78 | PDE4A (0.60) | TSHRMAPTLMNAPDE4APDE4B | |
| SCHEMBL10812154 | 0.78 | TSHR (0.68) | TSHRMAPTLMNAPDE4APDE4B | |
| SCHEMBL11122437 | 0.78 | TSHR (0.68) | TSHRMAPTLMNAPDE4APDE4B | |
| SCHEMBL14601551 | 0.78 | ALDH1A1 (0.68) | NPSR1MAPTLMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |