Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 3/20 | 0.51 |
| ▸ | MOGAT2 | Q3SYC2 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76535 | 0.88 | CYP2D6 (0.60) | LMNAACLYMOGAT2THRBCYP2D6 | |
| SCHEMBL7589345 | 0.79 | MEN1 (0.57) | LMNAACLYKMT2A | |
| SCHEMBL25450369 | 0.78 | CYP2D6 (0.53) | LMNAACLYCYP2D6CYP2C9KIF11 | |
| SCHEMBL12655168 | 0.78 | LMNA (0.58) | LMNAACLYMOGAT2THRBTSHR | |
| SCHEMBL5801171 | 0.78 | LMNA (0.61) | LMNATHRBTSHRKMT2AMGAT2 | |
| SCHEMBL7591285 | 0.77 | SLC40A1 (0.59) | LMNAACLYCYP2D6CYP2C9KMT2A | |
| SCHEMBL12459512 | 0.76 | LMNA (0.60) | LMNAACLYMOGAT2THRBKMT2A | |
| SCHEMBL6824081 | 0.76 | CYP2D6 (0.60) | LMNAACLYCYP2D6CYP2C9KMT2A | |
| SCHEMBL30161104 | 0.75 | CYP2D6 (0.50) | LMNAACLYCYP2D6CYP2C9KIF11 | |
| SCHEMBL25450235 | 0.75 | CYP2D6 (0.50) | LMNAACLYCYP2D6CYP2C9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | LMNA 4385/4885ACLY 713/4885MOGAT2 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.