Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5597742 | 0.98 | MAPT (0.57) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL11814444 | 0.86 | EPHX1 (0.54) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL14601747 | 0.85 | TMPRSS4 (0.49) | MAPTLMNAMEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL5597980 | 0.83 | TMPRSS4 (0.48) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL1431941 | 0.79 | EPHX1 (0.74) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL30977691 | 0.79 | EPHX1 (0.74) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8527587 | 0.79 | MAPT (0.64) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2705806 | 0.79 | MAPT (0.64) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL11511219 | 0.79 | LMNA (0.63) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL14459549 | 0.79 | KDR (0.70) | LMNAMEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | MAPT 3058/4885LMNA 4385/4885MEN1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.