Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | IL18 | Q14116 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700424 | 0.86 | PPARA (0.64) | PPARAMAPTPPARDALDH1A1SLC22A12 | |
| SCHEMBL22884963 | 0.84 | PPARA (0.55) | PPARAMAPTPPARDALDH1A1SLC22A12 | |
| SCHEMBL14468109 | 0.83 | PPARA (0.50) | PPARAMAPTPPARDALDH1A1SLC22A12 | |
| SCHEMBL1417805 | 0.80 | PPARA (0.49) | PPARAMAPTPPARDALDH1A1SLC22A12 | |
| SCHEMBL4692295 | 0.79 | PPARA (0.66) | PPARAMAPTPPARDALDH1A1RAB9A | |
| SCHEMBL16580097 | 0.77 | LMNA (0.52) | PPARAMAPTPPARDALDH1A1SLC22A12 | |
| SCHEMBL15460016 | 0.77 | MAPT (0.48) | PPARAMAPTPPARDALDH1A1PARP10 | |
| SCHEMBL22705635 | 0.77 | ALDH1A1 (0.49) | PPARAMAPTPPARDALDH1A1RAB9A | |
| SCHEMBL435736 | 0.77 | KIF11 (0.47) | PPARAMAPTPPARDALDH1A1PARP15 | |
| SCHEMBL9372364 | 0.76 | PPARA (0.72) | PPARAMAPTPPARDALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157479-B2 | Oxazol/thiazol-derivatives activators of the hPPAR-alpha receptor | GLAXO GROUP LIMITED (GB) | 2007-01-02 | — | — | US | disclosed |